JOT - 2026-06-01 - Journal Article
Rethinking Avascular Necrosis After Displaced Talus Fractures and Dislocations.
Frazer A, Ndoja S, Grad V, Fortin G, MacLeod M, Lawendy AR, Inculet C, Del Balso C, Schemitsch E, Sanders D
Topics
Key Takeaway
AVN developed in 38% of displaced talus fractures/dislocations, but 90% had <25% talar dome collapse and AVN did not independently drive secondary reconstructive surgery (25% overall SRS rate).
Summary Depth
Choose how much analysis to show on this article page.
Summary
This study examined whether AVN development after operatively treated talus fractures/dislocations (AO/OTA 81-A/B/C) predicts need for secondary reconstructive surgery and whether the Hawkins sign reliably predicts talar vitality. AVN occurred in 38% (30/79), but was the direct indication for SRS in only 6 of 20 SRS cases (30%), and AVN presence did not independently predict SRS. Nonanatomic reduction (p=0.033), older age (p=0.01), and greater number of incisions (p=0.001) were the significant predictors; timing of surgery <24 hours and anatomic reduction were not associated with AVN development.
Key Limitation
Single-center retrospective design with mean follow-up of only 32.5 months is insufficient to capture late talar collapse and progressive posttraumatic arthritis requiring SRS, likely underestimating the long-term clinical impact of AVN.
Original Abstract
OBJECTIVE
To investigate the relationship of avascular necrosis (AVN) of the talus with postoperative outcomes and to assess the utility of the Hawkins sign and its ability to predict talar vitality following talar fracture or dislocation.
DESIGN
Retrospective cohort study.
SETTING
Single center, academic, Level I Trauma center.
PATIENT SELECTION CRITERIA
Patients with talus injuries (AO/OTA 81-A, 81-B, 81-C) treated from 2007 to 2017 were included.
OUTCOME MEASURES AND COMPARISONS
Variables analyzed included anatomic location, fracture classification, timing of surgery, reduction quality, and the presence or absence of Hawkins sign. Outcomes measured included development of AVN, degree of collapse, union, posttraumatic arthritis, prognostic reliability of the Hawkins sign, and secondary reconstructive surgery (SRS). Data were analyzed using binary logistic regressions.
RESULTS
Seventy-nine patients were reviewed, 65% of which were male, with mean age of 37.7 years (range 18-83 years). Patients were followed for average of 32.5 months postsurgery. Of the 79 patients, 30 developed AVN (38%) and 20 of the 79 required SRS (25%). Of the 20 SRS cases, AVN was an indication for 6 cases (30%). Of the 30 AVN cases, 27 (90%) demonstrated less than 25% collapse of the talar dome, with 3 demonstrating more than 25% collapse. Age at the time of surgery and a higher number of incisions were associated with AVN (B = 0.051, P = 0.01 and B = 2.173, P = 0.001). Timing of surgery (<24 hours) and anatomic reduction were not associated with the development of AVN (B = 0.602, P = 0.286 and B = 0.641, P = 0.491). Nonanatomic reduction was associated with higher rates of SRS (B = -1.777, P = 0.033).
CONCLUSIONS
Radiographic evidence of AVN was common after fractures and dislocations of the talus, with 38% of patients in this study developing AVN. However, the development of AVN did not influence the rate of SRS at follow-up. This may be explained by the fact that most AVN patients (90%) had less than 25% collapse. Factors associated with AVN development included increased age at surgery and an increase in the number of incisions. The development of AVN had no detrimental clinical impact in this study.
LEVEL OF EVIDENCE
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.