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Archives of Orthopaedic and Trauma Surgery - 2026-08-10 - Journal Article

Effect of distal screw number on axial deformation and fragment-specific stability in AO/OTA 2R3 C2.1 distal radius fractures.

Dietz L, Spiegel C, Kohler FC, Biedermann U, Zderic I, Feist A, Gueorguiev-Rüegg B, Lenz M, Weschenfelder W

cadavericLOE Vn = 16 radii (8 matched pairs)N/A

Topics

handtrauma
PMID: 42573806DOI: 10.1007/s00402-026-06454-6View on PubMed ->

Key Takeaway

In an AO/OTA 2R3 C2.1 cadaveric fracture model, six distal screws reduced post-cyclic axial deformation and radial fragment-shaft translation compared to four screws (p=0.047 and p=0.028–0.045, respectively).

Summary Depth

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Summary

This study asked whether increasing distal screw number from four to six in volar locking plate fixation of AO/OTA 2R3 C2.1 fractures improves construct stability under cyclic loading. Nine matched cadaveric pairs were randomized to four- or six-screw 2.4-mm variable-angle locking plate constructs and subjected to 5,000 cycles at 150 N axial load with optical motion tracking. The six-screw group demonstrated significantly lower post-cyclic axial deformation (p=0.047) and lower radial fragment-shaft translation at both measurement time points (p=0.028; p=0.045), though rotational differences did not persist after cycling.

Key Limitation

The cadaveric model uses a standardized, idealized fracture pattern that does not replicate the variable comminution geometry and soft tissue contributions encountered clinically, limiting direct translation of the biomechanical thresholds to patient outcomes.

Original Abstract

PURPOSE

To investigate the biomechanical influence of distal screw number in palmar plate fixation of unstable intra-articular distal radius fractures with radiodorsal metaphyseal comminution.

METHODS

Nine matched pairs of cryopreserved human radii were prepared using a standardized AO/OTA 2R3 C2.1 fracture model with a defined radiodorsal metaphyseal defect zone. For each pair, specimens were randomized to palmar fixation using a 2.4-mm variable-angle locking plate with either four or six distal screws. After embedding, constructs were subjected to cyclic axial loading (150 N, 5,000 cycles) simulating early postoperative rehabilitation. Global axial deformation and fragment-specific three-dimensional interfragmentary motion were recorded using an optical motion-tracking system. Statistical analysis was performed using non-parametric tests (p < 0.05).

RESULTS

Two specimens from one donor pair were excluded, leaving 16 radii (8 pairs) for analysis. Bone mineral density and initial construct stiffness did not differ between groups. The six-screw configuration showed significantly lower axial deformation after cyclic loading (p = 0.047) and lower radial fragment-shaft translation at both time points (p = 0.028; p = 0.045). Radial fragment-shaft rotation was lower in the six-screw group at baseline (p = 0.018), but no rotational difference remained after cyclic loading. In the overall cohort, axial deformation decreased after cyclic loading (p = 0.015).

CONCLUSION

In this unstable intra-articular fracture model with radiodorsal metaphyseal comminution, six distal screws reduced post-cyclic axial deformation and radial fragment-shaft micromotion compared with four screws. The clinical relevance of these findings remains to be determined.