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JOA - 2026-08-24 - Journal Article

Collared, Uncemented Stems Markedly Reduce Periprosthetic Femoral Fracture Risk in Women ≥ 70 Years: A Swiss National Registry Study.

Ladurner A, Kramer M, Giesinger K, Zdravkovic V

database studyLOE IIIn = 32,874N/A (registry study; revision as endpoint, not reported as mean follow-up duration)

Topics

arthroplasty
PMID: 42637028DOI: 10.1016/j.arth.2026.08.037View on PubMed ->

Key Takeaway

Collared uncemented stems reduced periprosthetic femoral fracture revision risk by 92% versus collarless stems (0.1% vs 0.6%; aOR 0.08) in women ≥70 years undergoing THA.

Summary Depth

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Summary

This SIRIS registry study evaluated whether stem design features—specifically collar presence, offset, neck-shaft angle, and relative stem length—affect periprosthetic femoral fracture (PFF) revision risk in women ≥70 undergoing uncemented THA for OA between 2012 and 2024. Nine cementless stem models with >1,000 implantations each were analyzed via multivariable logistic regression against a cemented reference population. Collared stems demonstrated a dramatically lower PFF revision rate versus collarless stems (0.1% vs 0.6%; aOR 0.08, 95% CI 0.03–0.27), while offset, neck-shaft angle, and stem length showed no significant association with fracture risk.

Key Limitation

The registry lacks intraoperative data on canal fill, cortical contact quality, and surgeon volume, which are critical determinants of PFF risk that may confound the collar-versus-collarless comparison.

Original Abstract

INTRODUCTION

Uncemented total hip arthroplasty (THA) is associated with an increased risk of periprosthetic femoral fractures (PFF) in elderly women, yet its use continues to expand in this high-risk population. Stem design, particularly the presence of a collar, may influence the risk. However, sex-specific, large-scale registry data addressing this question remain limited. This study evaluated the association between stem design, design variants, and PFF risk in women aged ≥ 70 years undergoing uncemented THA.

METHODS

Data were obtained from the Swiss National Joint Registry (SIRIS). Women aged ≥ 70 years who underwent uncemented THA for osteoarthritis between 2012 and 2024 were included. There were nine cementless stem models with greater than 1,000 implantations each that were analyzed by design variant (collared versus collarless, standard versus high offset, varying neck-shaft angles (NSA), and relative stem length). A total of 32,874 patients were included (mean age 76 years, mean body mass index (BMI) 26.5). The THAs with cemented stem fixation served as a reference population. The primary outcome was revision for PFF; multivariable logistic regressions were used to adjust for patient- and implant-related factors.

RESULTS

The overall PFF revision rate was 0.5%, compared with 0.2% in the older, more medically vulnerable cemented group (P < 0.001). The PFF incidence varied substantially across uncemented stems (0.1 to 1.1%). Collared stems had a significantly lower PFF risk than collarless variants (0.1 versus 0.6%; adjusted odds ratio: 0.08, 95% confidence interval: 0.03 to 0.27, P < 0.001). Offset, neck-shaft angle, and relative stem length were not associated with fracture risk.

CONCLUSION

In women aged ≥ 70 years, uncemented THA was associated with a higher risk of PFF revision compared with cemented fixation. Within cementless designs, the presence of a collar was strongly associated with a reduced risk of PFF, whereas other design variants were not. These findings suggest that in elderly women, collared cementless stems may represent a safe uncemented alternative to cemented stem fixation.