Spine - 2026-09-07 - Journal Article
A Prospective Comparative Study of UBE-ULBD Versus Endo-ULBD for Lumbar Spinal Stenosis.
Liu W, Du Y, Wang Y, Li P, Kao Y, Zhao Y, Gao Y, Li Y
Topics
Key Takeaway
UBE-ULBD and Endo-ULBD produce equivalent 12-month clinical outcomes for Schizas grade C/D lumbar stenosis, with modified Macnab satisfaction rates of 90.9% vs 89.1% (P=0.92), though UBE-ULBD has shorter operative time and Endo-ULBD has shorter hospital stay.
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Summary
This RCT compared UBE-ULBD versus single-port Endo-ULBD in 110 patients with Schizas grade C/D single-level lumbar stenosis, randomized 1:1 with ITT and PP analysis. Both groups achieved significant improvement in VAS and ODI with no intergroup difference at 12 months; dural sac cross-sectional area expansion and facet preservation were equivalent (P>0.05). UBE-ULBD had shorter operative time (P<0.01) while Endo-ULBD had shorter hospital stay (P<0.01); one dural tear occurred in the Endo-ULBD group.
Key Limitation
Follow-up limited to 12 months precludes assessment of restenosis, late instability, or need for fusion conversion, which are the clinically meaningful long-term endpoints for any decompression-only strategy.
Original Abstract
STUDY DESIGN
Prospective, randomized controlled trial (RCT).
OBJECTIVE
To directly compare the clinical and radiological outcomes of Unilateral Biportal Endoscopic Unilateral Laminotomy for Bilateral Decompression (UBE-ULBD) versus single-port Endoscopic Unilateral Laminectomy for Bilateral Decompression (Endo-ULBD) for single-level lumbar spinal stenosis (LSS).
SUMMARY OF BACKGROUND DATA
While UBE-ULBD has emerged as an efficacious minimally invasive technique for degenerative LSS, the comparative efficacy and safety profile of Endo-ULBD remains comparatively underexplored. This study aims to bridge this knowledge gap by directly comparing these two endoscopic modalities.
METHODS
110 patients with Schizas grade C/D LSS were randomized to UBE-ULBD or Endo-ULBD (55/group). Primary outcomes included VAS, ODI, and modified Macnab criteria. Radiological outcomes focused on dural sac cross-sectional area (DSCSA) and facet preservation. All procedures were performed by the same senior surgeon. Analysis was conducted per ITT and PP principles, with a 12-month follow-up.
RESULTS
Both groups demonstrated significant clinical improvement (P<0.05). UBE-ULBD was associated with a shorter operative time (P<0.01), largely attributable to the ergonomic advantages of the dual-portal system and the use of a high-speed drill. Notably, a trephine was utilized exclusively in the Endo-ULBD group. Conversely, Endo-ULBD was associated with a shorter postoperative hospital stay (P<0.01), a difference potentially influenced by both technical and non-clinical factors. Radiological outcomes, including dural sac expansion and facet joint preservation rates, were comparable between groups (P>0.05). No significant intergroup differences were observed in VAS, ODI, or modified Macnab satisfaction rates at the 12-month follow-up (ITT: 90.9% in UBE-ULBD vs. 89.1% in Endo-ULBD, P=0.92; PP: 98.0% in UBE-ULBD vs. 94.0% in Endo-ULBD, P=0.92). One dural tear occurred in the Endo-ULBD cohort.
CONCLUSIONS
Both UBE-ULBD and Endo-ULBD proved safe and effective, yielding comparable clinical and radiological outcomes at the 12-month follow-up. Within the constraints of this study, both techniques represent viable options for minimally invasive decompression.