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Journal of Pediatric Orthopaedics - 2026-03-30 - Journal Article

Clinical Presentation and Patient-reported Function in Children With Sprengel's Deformity.

Lee J, Buttrick E, Vuillermin C, Wall L, Samora J, Shah AS, CoULD Study Group

prospective cohortLOE IIn = 59N/A (cross-sectional PRO collection at most recent preoperative visit)

Topics

pediatrics
PMID: 41906598DOI: 10.1097/BPO.0000000000003271View on PubMed ->

Key Takeaway

Children with Sprengel's deformity demonstrate mean shoulder abduction of 113° and forward elevation of 120°—significantly below normal—with PODCI Upper Extremity, Sports, and Global Function scores all reduced versus norms, regardless of bilateral or syndromic presentation.

Summary Depth

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Summary

This study characterized baseline clinical presentation and patient-reported function in children with Sprengel's deformity using the multicenter CoULD Registry (2014–2023). Shoulder abduction (113°) and forward elevation (120°) were significantly below normal, and PODCI Upper Extremity, Sports, and Global Function scores were significantly lower than population norms (P<0.05). Cavendish grade III was most prevalent (50.8%), higher Cavendish grade correlated with worse PODCI Transfer scores (P=0.011), and paradoxically, patients reported less anxiety and depression than normative populations (P=0.017 and 0.028).

Key Limitation

The small sample size (n=59) with 96.6% unilateral cases severely limits statistical power to detect meaningful differences between bilateral and unilateral presentations or between syndromic and non-syndromic subgroups.

Original Abstract

BACKGROUND

Sprengel's deformity is a rare congenital anomaly of the scapula, characterized by an elevated position, inferior tilting of the glenoid, and hypoplasia. Due to limited data on the impact of this congenital anomaly, the purpose of this study is to objectively characterize the initial clinical presentation and quantify both the range of motion and patient-reported function in children with Sprengel's deformity.

METHODS

Children with Sprengel's deformity were prospectively enrolled into the multicenter Congenital Upper Limb Differences (CoULD) Registry between 2014 and 2023. Shoulder range of motion and patient-reported outcomes (PROs) data were collected from the patient's most recent preoperative follow-up and compared with normative values. PROs included the Pediatric Outcomes Data Collection Instrument (PODCI) and PROMIS Upper Extremity, Pain Interference, Depression, Anxiety, and Peer Relations domains. Univariate analysis was performed to compare unilateral versus bilateral presentation, non-syndromic versus syndromic association, and Cavendish grades.

RESULTS

In total, 59 patients (52.5% female) were included with a median age of 5.9 years. Most patients presented with unilateral involvement (96.6%) and without an associated syndrome (78.0%). Cavendish grade III was the most common (50.8%) presentation. Average shoulder abduction (113 degrees) and forward elevation (120 degrees) were significantly less than the normal range (P<0.001). Children with Sprengel's deformity reported less anxiety and depression than the normative population (P=0.017 and 0.028, respectively). Patients scored significantly lower on PODCI Upper Extremity Function, Sports, and Global Function modules than the normative population (P<0.05). PODCI Transfer sub-scores significantly varied by Cavendish classification (P=0.011). Neither bilateral presentation nor syndromic association significantly affected other PROs (P>0.05).

CONCLUSIONS

Children with Sprengel's deformity have decreased shoulder range of motion, specifically abduction and forward elevation. Regardless of bilateral or syndromic presentation, patients generally demonstrated significantly lower physical function and sports abilities, but reported less anxiety and depression than population norms. A higher Cavendish grade was associated with worse transfer and mobility function.

LEVEL OF EVIDENCE

Therapeutic level II.