Arthroplasty
meta-analysis
LOE I
n = 11 studies, median cases per study 164
N/A if not reported.
Sheth N, McCall M · … · Wilson JM
Key Takeaway: Isolated component revision TKA yields re-revision rates statistically equivalent to full-component revision (OR 1.36, 95% CI 0.96–1.95, P=0.094) while significantly reducing operative time (SMD 2.85, P<0.001).
Shoulder & Elbow
cost-effectiveness
LOE II
n = N/A (decision tree model; systematic review inputs from Level I-II studies)
5-year time horizon
Saad Berreta R, Badin D · … · Srikumaran U
Key Takeaway: RCR with concomitant SAD dominates isolated RCR over 5 years, costing $1,145 less ($33,448 vs $34,593) while yielding 0.011 more QALYs and remaining cost-effective in 99.28% of Monte Carlo simulations.
Arthroplasty
prospective cohort
LOE II
n = 351 (cryoneurolysis n=171, control n=180)
6 months
Ng MK, Lin JH · … · Mont MA
Key Takeaway: Preoperative cryoneurolysis reduced opioid use in the first week after TKA by 31% (RR 0.69) and cut persistent opioid use (>3 months) by 60% (RR 0.40) compared to controls.
Sports Medicine
prospective cohort
LOE II
n = 25 (10 eumenorrheic, 15 anovulatory controls)
4 time points over 1 month
Argentieri E, Hamilton TW · … · Potter HG
Key Takeaway: Eumenorrheic women show a significant 1.0 ms increase in ACL long T2* from preovulatory to postovulatory phase (P=.015, Cohen d=0.51), while anovulatory controls show no temporal change, implicating hormone-driven tissue hydration shifts as a measurable ACL vulnerability biomarker.
Trauma
prospective cohort
LOE II
n = 73
EMG performed within first week after pin removal at 1 month postoperatively.
Kandemir İ, İğrek S · … · Eceviz E
Key Takeaway: EMG detected subclinical ulnar nerve axonal injury in 19.2% of pediatric patients after CRPP for Gartland III/IV supracondylar humerus fractures, with posterior medial pin entry site carrying an OR of 6.745 for injury.
Spine
prospective cohort
LOE II
n = 721
2 years
Horiuchi Y, Nagoshi N · … · Watanabe K
Key Takeaway: In 721 CSM patients, binary preoperative intramedullary T2 signal intensity was not independently associated with worse JOA recovery rate, JOACMEQ effectiveness, or SF-36 at 2 years after multivariable adjustment.
Sports Medicine
prospective cohort
LOE II
n = 64
Minimum 2 years; median conversion to surgery at 6 months (IQR 3–8 months) for surgical group.
Nonaka S, Hatayama K · … · Chikuda H
Key Takeaway: Nonoperative MMPRT management yields significant clinical improvement (NRS 7.6→1.3 at 6 months) despite concurrent structural deterioration, with varus alignment >5.5° (AUC 0.742) predicting conversion to surgery in 23.4% of patients.
Shoulder & Elbow
retrospective cohort
LOE III
n = 432
2016–2024 (up to 8 years); time-to-event analysis, exact mean not reported.
Mousavi SZ, Buettner C · … · Srikumaran U
Key Takeaway: Only 39.7% of guideline-eligible women received preoperative DXA screening before TSA, and current tobacco use conferred a 14.87-fold increased postoperative fragility fracture risk.
Trauma
retrospective cohort
LOE III
n = 201 (JBJS n=153, CORR n=48)
N/A
Parisien R
Key Takeaway: In 87.6% of 201 orthopaedic articles, Discussion sections were more epistemically cautious than Abstracts, with Discussion hedge density 2.8× higher and only 6% of Abstracts acknowledging any study limitations.
Arthroplasty
retrospective cohort
LOE III
n = 4,294 (2,147 per propensity-matched cohort)
2 years
Rteil A, Mzeihem M · … · Amirouche F
Key Takeaway: Robotic-assisted THA reduced 1-year dislocation by half (0.9 vs 1.8%; OR 2.07) and 2-year revision rate by nearly half (2.0 vs 3.7%; HR 1.9) compared to manual THA in patients with lumbar fusion or stiff spine.
Shoulder & Elbow
systematic review
LOE III
n = 16 systematic reviews and meta-analyses
N/A
Al-Badaineh M, Josan H · … · Khan M
Key Takeaway: Spin was present in 81.3% of systematic review abstracts on patch-augmented rotator cuff repair, with each AMSTAR-2 methodological flaw associated with 61% more spin types (IRR 1.61; 95% CI 1.08–2.49).
Shoulder & Elbow
retrospective cohort
LOE III
n = 139
1 year
Banfield NF, Puckett HD · … · Cunningham BP
Key Takeaway: In 139 aTSA patients, implants accounted for 49% of total episode-of-care cost ($13,301 mean), and ASC setting reduced cost by $2,847 without a corresponding improvement in 1-year ASES scores.
Arthroplasty
systematic review
LOE III
n = 6 studies, 33,091 patients (30,549 aged ≥40)
Minimum 2 years; up to 5 years reported across included studies.
Son H, Blackman B · … · Ayeni O
Key Takeaway: Hip arthroscopy in patients ≥40 years yields MCID-exceeding functional improvements at 2 years but carries a 2-year THA conversion rate of 9–13% and a 5-year conversion rate up to 20.2%.
Spine
retrospective cohort
LOE III
n = 256 (46 4-level, 210 3-level)
Minimum 1 year postoperative PROMs; 30-day surgical outcomes.
Lee Y, Dalton J · … · Schroeder GD
Key Takeaway: 4-level ACDF carries a higher dysphagia rate (20% vs. 8.6%) and 30-day ED visit rate (6.5% vs. 0%) compared to 3-level ACDF, but produces equivalent PROM improvements at 1 year.
Arthroplasty
systematic review
LOE III
n = 10 studies, 2730 hips (1580 repairs, 1150 debridements)
Variable; subgroup analyses stratified at <5 vs ≥5 years; specific mean not reported.
Bohn DS, Bigarella LG · … · Lima DJL
Key Takeaway: Arthroscopic labral repair reduces conversion to THA by 44% compared to debridement (3.5% vs 7.4%; RR 0.56, 95% CI 0.37–0.84) across 2730 hips at long-term follow-up.
Sports Medicine
retrospective cohort
LOE III
n = 579
N/A
Lerjefors E, Cristiani R · … · Stålman A
Key Takeaway: MRI detected ramp lesions in 43.2% of ACL-injured knees, but only 9.8% were confirmed arthroscopically, with Greif type 1 and 2 lesions showing 0% surgical correlation.
Arthroplasty
retrospective cohort
LOE III
n = 34,584
90 days
Haziza S, Greenberg M · … · Abdo ZE
Key Takeaway: Extended oral antibiotic prophylaxis after primary TKA was associated with nearly 3-fold higher 90-day PJI rates (1.99% vs. 0.72%) in a propensity-matched cohort of 34,584 patients.
Shoulder & Elbow
retrospective cohort
LOE III
n = 208 shoulders (98 aTSA, 110 rTSA); 36 matched pairs after propensity score matching
Minimum 2 years (2017–2023).
Harkin W, Shen A · … · Garrigues GE
Key Takeaway: In propensity score-matched patients with Walch B2/B3 glenoids, aTSA with a posterior augmented glenoid and rTSA yield equivalent 2-year PROMs (ASES 87.8 vs 88.6, p=0.79), but aTSA produces greater external rotation (47.7° vs 39.3°, p<0.001) and higher radiolucency rates (41.9% vs 9.3%, p<0.001).
Arthroplasty
retrospective cohort
LOE III
n = 3,577
N/A if not reported.
Salazar C, Shankar V · … · Kamara E
Key Takeaway: BMI ≥ 40 independently predicted return to OR (HR 1.63) and infection (OR 2.94) after primary THA, while BMI 30–39.9 carried no significantly elevated risk versus BMI <30.
Shoulder & Elbow
retrospective cohort
LOE III
n = 86 (43 matched pairs)
Mean 4.7 ± 2.2 years (range 2.1–12.8 years)
Martinez-Catalan N, García-Rubio C · … · Foruria AM
Key Takeaway: Cement-augmented locking plate fixation (ORIF-LPc) yielded superior external rotation (49° vs. 27°, p<0.001) compared to Delta Xtend rTSA for complex proximal humerus fractures in elderly patients, with equivalent Constant Scores, complication rates (21% vs. 19%), and revision rates (7% vs. 9%) at mean 4.7-year follow-up.
Trauma
retrospective cohort
LOE III
n = 67
Minimum 6 months; exact mean not reported.
Luther L, Maxson R · … · Mitchell PM
Key Takeaway: Multilevel transsacral fixation (MAT) reduced treatment failure in vertically unstable pelvic ring injuries to 2.6% versus 48.3% with single-level or SI-screw-only constructs (P<0.001).
Shoulder & Elbow
retrospective cohort
LOE III
n = 831 (577 with preoperative CT)
Minimum 1 year postoperative (DEXA capture rate assessed at 1 year); exact mean follow-up not reported.
Wang Z · … · Aibinder W
Key Takeaway: Among 199 high-risk TSA patients (FRAX major >20% or hip >3%), only 16% received 1-year postoperative DEXA and 13% were on osteoporosis medications, while humeral head HU was significantly lower in high-risk versus low-risk patients (28.5 vs 50.1 HU, p<0.001).
Trauma
retrospective cohort
LOE III
n = 208 (OP: 29, AP: 125, SP: 54)
N/A if not reported.
Rossbach K, Mau M · … · Haller J
Key Takeaway: Occult infected nonunions (culture-positive but FRI-criteria-negative) achieved successful union after index surgery in 79.3% of cases, comparable to aseptic nonunions (72.8%) and significantly better than septic nonunions (50.0%, p=0.004).
Arthroplasty
retrospective cohort
LOE III
n = 1,562 TKAs (142 SID vs 1,420 controls, propensity-score-matched)
90 days post-discharge
Nakla A, Aubin PM · … · Wu M
Key Takeaway: In metabolic syndrome TKA patients, smart implantable device use reduced 90-day hospital readmission from 11.1% to 5.6% and ED visits from 16.6% to 9.9%.
Pediatric Orthopaedics
retrospective cohort
LOE III
n = 25 SCFE patients plus age- and sex-matched obese and healthy controls
Mean 24 months
Kurk MB, Albayrak K · … · Akpinar E
Key Takeaway: D-dimer levels were significantly higher in SCFE patients versus obese and healthy controls (P<0.001) and correlated with contralateral slip development, improving contralateral slip prediction AUC from 0.80 to 0.87 when added to Southwick angle difference and MOBS, though this AUC gain was not statistically significant (P=0.18).
Arthroplasty
retrospective cohort
LOE III
n = 70
Mean not specified; outcomes reported at 3 months and 1 year.
Khury F, Ehlers M · … · Schwarzkopf R
Key Takeaway: Revision TKA preserved functional limb length in 68.6% (contralateral reference) and 47.1% (pre-rTKA reference) of cases, with coronal alignment preserved in 64.3%; PROM improvements were statistically comparable across all limb-length and alignment categories at one year.
Sports Medicine
prospective cohort
LOE III
n = 82
Serial imaging at 6, 12, and 24 months post-surgery.
Barnes DA, Murray CJ · … · Fleming BC
Key Takeaway: Meniscal morphological and signal intensity abnormalities in the anterior medial and lateral menisci persist at 24 months post-ACL surgery, failing to normalize toward the contralateral limb across all three time points.
Arthroplasty
retrospective cohort
LOE III
n = 168,493 (143,427 non-collared; 25,066 collared)
Up to 10 years (Kaplan-Meier analysis).
Oettl FC · … · Hoch A
Key Takeaway: Collared cementless femoral stems demonstrated a 42% reduced risk of aseptic femoral loosening (HR 0.58) and 35% reduced all-cause revision risk (HR 0.65) at 10 years compared to non-collared stems in 168,493 primary THAs.
Arthroplasty
retrospective cohort
LOE III
n = 160
Median 15 years (IQR 10–21 years)
Park YL, Wackerle AM · … · Hughes JD
Key Takeaway: MAT survivorship declines to 52% at 25 years, and after adjusting for age and cartilage grade, female sex is an independent predictor of graft failure (p=0.04).
Arthroplasty
database study
LOE III
n = 11,965
30 days and 2 years
Patel D, Gay S · … · Mutch J
Key Takeaway: In BMI ≥40 patients undergoing bilateral TKA, staged versus simultaneous surgery reduced 30-day composite complications (OR 0.18), two-year aseptic loosening (OR 0.24), and all-cause revision (OR 0.13).
Sports Medicine
retrospective cohort
LOE III
n = 62 (31 STA, 31 propensity-matched controls)
Mean 3.8 years (range 3.1–5.0)
Wang Y, Zhang Y · … · Gong X
Key Takeaway: Suture tape augmentation of hamstring autograft ACLR in patients with high internal rotational tibial subluxation (>5.8 mm) reduced graft failure to 0% versus 12.9% in matched controls at mean 3.8-year follow-up.
Arthroplasty
retrospective cohort
LOE III
n = 224,954 (37,992 minority; 186,962 White)
N/A
Ogu E · … · Sambandam S
Key Takeaway: Minority THA patients have 47% lower odds of receiving robotic-assisted THA compared to White patients (OR 0.53), with Black/African American patients facing the greatest disparity (OR 0.41), persisting after propensity score matching.
Spine
meta-analysis
LOE III
n = 19 studies, 5,753 patients
Range 3–120 months across included studies; pooled mean not reported.
Elgeadi G · … · de Pedro M
Key Takeaway: Endoscopic spinal surgery in patients ≥80 years achieved VAS leg pain, VAS back pain, ODI, and Modified Macnab success rates statistically comparable to patients <80 years across 5,753 patients with no significant excess in complications.
Arthroplasty
systematic review
LOE III
n = 160 studies from 31 countries
N/A
Valdivia LM, Farid CJ · … · Hayden BL
Key Takeaway: Of 160 RCTs informing the 2021 AAOS hip fracture CPG, 90.6% reported no language, race, or ethnicity data, and only 3.2% used culturally adapted PROMs.
Spine
meta-analysis
LOE III
n = 28 studies, 4,560 patients
N/A (not uniformly reported across included studies)
Patel S, Nischal SA · … · Prasad SK
Key Takeaway: Opportunistic CT Hounsfield unit measurement at the upper instrumented vertebra achieves pooled AUC 0.86 for predicting proximal junctional failure, which occurred in 23.3% of 4,560 ASD patients across 28 studies.
Arthroplasty
retrospective cohort
LOE III
n = 180
4 weeks postoperative
Kugo M, Kumagai K · … · Imai S
Key Takeaway: JKOM score at two weeks post-TKA correlated with four-week JKOM score at r=1.00, identifying early pain and functional impairment as predictors of delayed recovery by four weeks.
Trauma
systematic review
LOE III
n = 6 studies, 2,317 patients
Range 18 weeks to 3 years across included studies.
Hübner CT, Anranter A · … · Teuben MP
Key Takeaway: Among 2,317 solid organ transplant recipients treated operatively for fractures, the pooled infection rate was 10% and 90-day readmission rate was 20%, which the authors argue are not substantially elevated compared to the general fracture population.
Spine
retrospective cohort
LOE III
n = 139
12 months postoperative
Lee Y, Baek G · … · Kepler C
Key Takeaway: Patients with ≥1 year of myelopathy symptoms had worse absolute NDI and VAS Neck scores postoperatively but achieved MCID at comparable or higher rates versus those with <1 year of symptoms, with no difference in mJOA recovery at any time point.
Sports Medicine
prospective cohort
LOE III
n = 449
N/A if not reported.
Noailles T, Bouguennec N · … · Toanen C
Key Takeaway: In 449 ACL reconstruction patients with ramp lesions, Thaunat classification type significantly correlated with both pathological meniscal mobility (79.7% of cases, p<0.01) and number of sutures required (p<0.01), supporting a lesion-specific repair strategy.
Spine
retrospective cohort
LOE III
n = 141 (from 5,144 AIS patients screened; 148 complications total)
Mean 5 years (complications detected mean 21.5 months postoperatively, SD ±22.6 months)
Plachta SM, Samdani AF · … · Harms Study Group
Key Takeaway: Among 141 AIS patients with instrumentation-related complications, 54% were managed conservatively with comparable 5-year SRS-22 scores to revision surgery patients, except in the broken instrumentation subgroup where revision produced significantly higher domain scores.
Sports Medicine
retrospective cohort
LOE III
n = 841 knees (786 isolated ACLR, 55 ACLR + LMPR repair)
Median 46.0 months
Carrozzo A, Bérard É · … · Cavaignac E
Key Takeaway: Concomitant all-inside lateral meniscus posterior root repair during ACLR showed no significant difference in graft rerupture-free survival versus isolated ACLR (9.1% vs. 5.2%, HR 1.5, 95% CI 0.6–3.9), while professional athlete status independently doubled rerupture risk (HR 2.8).
Spine
retrospective cohort
LOE III
n = 235 patients, 4,518 screws
N/A
Wolf JJ, Shobode M · … · Kadado A
Key Takeaway: In 235 AIS patients with 4,518 screws, 7.8% triggered low-threshold EMG alerts (≤8 mA), yet 79.2% were retained without neurologic consequence, and neuromonitoring alert rates were identical between LTS and non-LTS groups.
Pediatric Orthopaedics
retrospective cohort
LOE III
n = 56 (26 Ti-Robot, 30 freehand)
Minimum 1 year.
Ma Y, Yang H · … · Lyu X
Key Takeaway: Ti-Robot-assisted fixation of pediatric femoral neck fractures improved screw parallelism and reduced intraoperative fluoroscopy frequency and radiation dose compared to freehand technique, but showed no difference in Harris Hip Score, complication rate, or healing time at minimum 1-year follow-up.
Spine
retrospective cohort
LOE III
n = 3,534 HIV-positive patients matched to 7,064 HIV-negative controls
10 years (database period 2010–2023)
Kishan A, Khela HS · … · Jankowski PP
Key Takeaway: HIV-positive patients undergoing thoracic or lumbar fusion showed no significant difference in 10-year all-cause revision surgery compared to matched controls (HR=0.96, 95% CI: 0.75–1.22).
Arthroplasty
retrospective cohort
LOE III
n = 241
N/A
Kawaguchi K · … · Young S
Key Takeaway: CT-based CPAK measurements yield a more varus MPTA (86.7° vs 87.1°), more valgus LDFA (87.1° vs 87.8°), and higher frequency of Type II phenotype (45.2% vs 33.2%) compared to long-leg radiographs, with discrepancies driven by preoperative coronal deformity and flexion contracture.
Spine
database study
LOE III
n = N/A (aggregate CMS billing data across all Medicare FFS billing episodes for CPT 63047, 2013–2023)
N/A
Dinesh A, Hirpara A · … · Rajan PV
Key Takeaway: From 2013 to 2023, inflation-adjusted Medicare FFS reimbursement for lumbar laminectomy (CPT 63047) fell 17.0% ($783 to $649) while population-based utilization declined 18.1% and the performing surgeon workforce shrank 16.6%.
Trauma
systematic review
LOE III
n = 8 studies (total patient N not reported)
N/A
Boever J, Unglaub F · … · Kußmaul AC
Key Takeaway: Across 8 comparative studies, PRC demonstrated superior range of motion and lower complication rates versus 4CF, while 4CF yielded higher grip strength, with no high-quality RCT definitively favoring either procedure.
Spine
retrospective cohort
LOE III
n = 516 (273 L4-5, 122 L5-S1, 121 L4-S1)
N/A if not reported.
Nguyen KT, Bansal A · … · Nemani VM
Key Takeaway: Segmental alignment criteria classified only 42.3% of L5-S1 and 33.6% of L4-S1 fusions as adequately aligned, versus 82.7% and 72.0% by PI-LL alone, exposing a systematic masking effect of global metrics.
Arthroplasty
retrospective cohort
LOE III
n = 74
Mean 45.4 months
Afacan MY, Gurcinar MG · … · Kaynak G
Key Takeaway: In THA for DDH-related OA, Crowe III-IV hips demonstrate a persistent valgus-oriented postoperative lower-limb alignment profile with FDR-significant changes in 7 radiographic parameters (mLDFA, aLDFA, mMPTA, JLCA, GO, HKA, FMMA) that do not fully normalize to the contralateral reference limb at mean 45.4 months.
Spine
retrospective cohort
LOE III
n = 1,986 octogenarians (993 per matched cohort); additional age-stratified comparisons with 50–69 year cohorts
Outcomes assessed at 0–2 weeks, 6–24 weeks, and 1–2 years postoperatively.
Hamad CD, Wiener J · … · Sheppard WL
Key Takeaway: Multi-level ACDF in octogenarians carries a 44% higher relative risk of acute dysphagia versus single-level (11.5% vs 8.0%, RR 1.44), and octogenarians have 1.45–1.71× higher early dysphagia rates than patients aged 50–69 regardless of operative extent.
Shoulder & Elbow
Journal Article; Randomized Controlled Trial; Comparative Study
Fedorka CJ, Tornberg HN · … · Dodson G
Key Takeaway: Summary unavailable from AI response.
Sports Medicine
systematic review
LOE IV
n = 9 studies, 347 patients
N/A if not reported.
Kahlon H, Blackman B · … · Kay J
Key Takeaway: Medial patellofemoral complex reconstruction (MQTFLR + MPFLR) achieves a 1.6% redislocation rate and 88.5–100% return to sport across 347 patients with recurrent patellar instability.
Arthroplasty
retrospective cohort
LOE IV
n = 17
N/A if not reported.
Kumar V, Kabra A · … · Gamanagatti S
Key Takeaway: A preoperative algorithm using CTA with selective endovascular intervention (balloon catheter or arterial coiling) in 13 of 17 revision THA patients with intra-pelvic implant migration resulted in zero major vascular injuries and mean blood loss of 1,310 mL.
Pediatric Orthopaedics
retrospective cohort
LOE IV
n = 50
Mean 3.0 years (range 1.1–5.3 years)
Brown MW, Park AM · … · Vitale MG
Key Takeaway: Rigo Chêneau orthosis in-brace correction ≥45% predicted treatment success with 88% success rate vs. 41% below that threshold (AUC=0.79), and 86% of patients avoided surgery at mean 3-year follow-up.
Shoulder & Elbow
case series
LOE IV
n = 50
N/A (pre- vs. postoperative MRI comparison; interval not specified)
So SP · … · Jeon IH
Key Takeaway: Arthroscopic Bankart repair shifts mean humeral head anteroposterior translation posteriorly by 0.91 mm (0.59 mm preoperatively to 1.50 mm postoperatively, p<0.001) on static axial MRI.
Trauma
retrospective cohort
LOE IV
n = 49 (21 augmentation, 28 control)
Mean 33.7 months (range 4.2–118.6 months)
Katzir A, Klinger CE · … · Ricci WM
Key Takeaway: CC suture Endobutton augmentation added to plate fixation achieved 100% union in displaced lateral clavicle fractures versus 92.8% without augmentation, but this difference was not statistically significant (p=0.19) in this underpowered series of 49 patients.
Shoulder & Elbow
systematic review
LOE IV
n = 10 comparative studies, 1,757 patients
Mean 24.9 months (cortical button), 26.6 months (suture anchor)
Nadeem SM, Yousafzai H · … · Khan M
Key Takeaway: Cortical button and suture anchor fixation for distal biceps repair yield equivalent re-rupture rates (2.9% vs 4.1%, RR 0.78, 95% CI 0.39–1.55) and LABCN neuropraxia rates (24.4% vs 22.7%, RR 1.12) across 1,757 patients.
Pediatric Orthopaedics
systematic review
LOE IV
n = 409 studies
N/A
Sonnier JH, Patel NM · … · Wolf SF
Key Takeaway: Across 409 pediatric sports medicine studies, female athletes comprised only 36% of participants on average, with single-sport studies enrolling only-female cohorts at half the rate of only-male cohorts (15.4% vs. 48.7%).
Shoulder & Elbow
systematic review
LOE V
n = N/A
N/A
Sheth M · … · Nagda S
Key Takeaway: In elderly patients with anterior glenohumeral dislocation, glenoid fractures >25% of glenoid width with humeral subluxation warrant fixation, and reverse shoulder arthroplasty is preferred over soft-tissue repair when healing potential is limited or preexisting degenerative changes are present.
Arthroplasty
Journal Article
Tse S, Lisacek-Kiosoglous AB · … · Haddad FS
Key Takeaway: Summary unavailable from AI response.
Arthroplasty
systematic review
LOE V
n = N/A
N/A
Sanghavi S · … · Sheth N
Key Takeaway: A structured diagnostic worksheet for failed THA systematizes evaluation across all contemporary failure modes, though no outcome data are reported to validate its clinical impact.
Pediatric Orthopaedics
Not available
LOE NOT REPORTED
n = Not reported
Not reported
Raj V · … · Pandey RK
Key Takeaway: Abstract not available — see the original article for details.
General
survey
LOE V
n = 400 queries and associated sources
N/A
Allen M, Beluzo B · … · Mulcahey MK
Key Takeaway: 79.3% of online biceps tenodesis resources exceed recommended 6th-8th grade reading levels, with a mean Flesch-Kincaid Grade Level of 9.8 and Gunning Fog Index of 13.7.
Sports Medicine
biomechanical
LOE V
n = N/A (murine model; C57BL/6J, PDGFRα-GFP reporter, and inducible HIF-1α knockout mice)
6 weeks post-injury (assessed at 1, 2, and 6 weeks)
Zhang H, Lee A · … · Liu X
Key Takeaway: FAP cell-specific HIF-1α knockout in a murine rotator cuff tear model increased fibrosis by 157% (4.43% vs 1.72%) and reduced myofiber cross-sectional area by 44% (664 vs 1196 µm²), identifying HIF-1α as a pro-adipogenic, anti-fibrotic regulator in rotator cuff muscle degeneration.
Trauma
cadaveric
LOE V
n = 10 paired cadaveric tibias (20 tibias total)
N/A
McDonald C, Atkinson C · … · Hand TL
Key Takeaway: Intentionally eccentric proximal-to-distal distal interlock drilling in cadaveric tibias produced mean coronal valgus of 6.0° and sagittal procurvatum of 5.8°, with up to 9.8 mm of axial distraction.
Sports Medicine
systematic review
LOE V
n = N/A (scoping review; exact number of included studies not reported in abstract)
N/A
Tewari K, Liu TP · … · Kremen TJ
Key Takeaway: 67% of publications on six emerging peptides (BPC-157, TB-500, CJC-1295, MK-677, ipamorelin, GHK-Cu) used preclinical animal models, and no peptide has sufficient human trial data to support clinical use in musculoskeletal recovery.
Foot & Ankle
retrospective cohort
LOE IV
n = 28
N/A
Nakajima H, Yamaguchi S · … · Ohtori S
Key Takeaway: The inferior fascicle attachment of the AITFL demonstrates the highest bone density on both the tibial (509.1 HU) and fibular (527.7 HU) sides, identifying it as the optimal anchor insertion site for syndesmotic augmentation.
Foot & Ankle
cadaveric
LOE V
n = 7 cadaveric specimens
N/A
Roward L, Reynolds Z · … · Jd Adams JD
Key Takeaway: Suture button fixation improved intentional syndesmotic malreduction by a mean 3 mm of translation and 10° of rotation, with no significant difference between quadricortical and tricortical placement (P=0.27 and P=0.227, respectively).
Foot & Ankle
case series
LOE IV
n = 51
Mean 58.2 months (±27.9)
Suer O, Eyceyurt RS · … · Kayali C
Key Takeaway: Sinus tarsi approach for Sanders type IV calcaneal fractures achieved a mean AOFAS hindfoot score of 81 and Böhler angle restoration from -6.4° to 22.4° at mean 58.2-month follow-up with a 14% reoperation rate and zero deep infections.
Pediatric Orthopaedics
database study
LOE V
n = 3,462 articles
N/A
Koçak M · … · Ömeroğlu H
Key Takeaway: A bibliometric analysis of 3,462 DDH publications from 2000–2025 found that North American and Western European institutions dominate citation impact despite lower publication volumes than Asian institutions, with the USA occupying the central node in the global collaboration network.
Trauma
biomechanical
LOE V
n = N/A (single cadaveric CT-derived finite element model)
N/A
Den S, Ueda K
Key Takeaway: In AO/OTA 31A2.2 intertrochanteric fractures, interfragmentary motion plateaus at nail lengths ≥260 mm, with no significant association between nail length and implant stress under simulated stair-climbing loads.
Trauma
systematic review
LOE V
n = N/A
N/A
Inui T
Key Takeaway: Anterior malreduction lacking anteromedial cortical contact carries an adjusted odds of cut-out comparable to a tip-apex distance ≥20 mm, establishing it as an equally important modifiable intraoperative target.
Hand & Wrist
cadaveric
LOE V
n = 16 radii (8 matched pairs)
N/A
Dietz L, Spiegel C · … · Weschenfelder W
Key Takeaway: In an AO/OTA 2R3 C2.1 cadaveric fracture model, six distal screws reduced post-cyclic axial deformation and radial fragment-shaft translation compared to four screws (p=0.047 and p=0.028–0.045, respectively).
Foot & Ankle
systematic review
LOE V
n = 22 studies, 289 patients
Weighted mean 25 months
Nogueira P, Patel A · … · Soares S
Key Takeaway: Patient-specific 3D-printed porous titanium implants for complex foot and ankle reconstruction achieved 92% limb salvage and 89% union across 289 patients, but carried a 26% reoperation rate driven by deep infection.
Sports Medicine
systematic review
LOE V
n = N/A
N/A
Ozeki N, Koga H
Key Takeaway: Anatomic ACL reconstruction has evolved from isometric single-bundle transtibial techniques toward individualized, dual-bundle and rectangular-tunnel morphology-based strategies that address both anterior and rotational instability, with concomitant meniscal pathology, remnant preservation, lateral extra-articular augmentation, and tibial slope correction now recognized as integral components.